name

PRODUCT

천연물에서 기능성소재를 개발하여 상품화하는 전문지식과 기술력으로 천연바이오산업의 미래를 개척해 나아갑니다
Quercus Acuta Thunb
Discover the beauty of nature's gifts
Quercus acuta Thunb. fruit extract

Quercus Acuta Thunb Fruit Extract is a patented formulation designed to prevent skin aging caused by ultraviolet (UV) exposure.
Research published in SCIE journals has demonstrated that this extract effectively blocks various pathways of photoaging, which contributes to 80% of facial skin aging, thereby aiding in wrinkle improvement. Additionally, as a top species for carbon storage, it represents a clean beauty cosmetic ingredient that supports the coexistence of human and natural ecosystems, embodying significant social value.

Exclusivity

Country registration number Patent Title
South Korea 10-2147623 Cosmetic composition for preventing and improving skin aging caused by ultraviolet rays containing Quercus acuta Thunb. extract

Contract Cultivation

We capture the pure vitality of Wando’s pristine nature just as it is.
Wando, the only subtropical arboretum in Korea and the largest subtropical forest habitat, preserves the unique natural conditions where mountains and seas converge.
We exclusively harvest from the largest Quercus acuta Thunb tree forest in Korea, located within Wando Arboretum.

Approval

Completed registration of cosmetic ingredients with Korean (KCA) and international (ICID) authorities
Currently undergoing efficacy testing for wrinkle improvement to obtain approval for functional cosmetics from the Ministry of Food and Drug Safety

Mechanism of Action

Blocked various pathways of skin photoaging

Protected HaCaT keratinocytes from UVB-induced damage and inhibited collagen degradation
Inhibited UVB-induced keratinocyte apoptosis
Inhibited the reduction of pro-collagen type I production caused by UVB
Suppressed the increase in intracellular ROS induced by UVB
Enhanced DPPH radical scavenging activity
Increased ABTS radical scavenging activity
Inhibited the production of MMP-1 in UVB-exposed keratinocytes
Suppressed UVB-induced phosphorylation of the MAPK pathway (ERK)
Inhibited UVB-induced phosphorylation of AP-1 (c-jun)
Inhibited UVB-induced phosphorylation of AP-1 (c-Fos)BMC Complement Med Ther. 2022, 22:6.

Promoted the production of collagen and elastin

Increased collagen production in fibroblasts by 143%P&K skin research center / 2024.1.2~2024.1.24
Inhibited elastase by 72%P&K skin research center / 2024.4.30~2024.5.8

Improved the appearance of crow's feet wrinkles

Analysis with the Visiometer for eye area skin showed improvements in 5 wrinkle parameters compared to the control groupR1, R2, R3, R4, R5: Reduction rates after 8 weeks (P＜0.01)KTR report TEK-2020-000581
The PRIMOS measurements and analysis showed improvements in three wrinkle parameters compared to the control groupRa, Rq, Rmax: Reduction rates after 8 weeks (P＜0.05)KTR report TEK-2020-000581

Recommended dosage

~ 0.5%